HIV AIDS: Difference between revisions
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[https://www.nature.com/articles/d42859-018-00008-6 by Zoltan Fehervari 28/11/18 nature portfolio] | [https://www.nature.com/articles/d42859-018-00008-6 by Zoltan Fehervari 28/11/18 nature portfolio] | ||
AIDS was first described as a new disease in 1981 (MILESTONE 1), and the causative lentivirus that came to be known as HIV-1 was identified a couple of years later (MILESTONE 2). However, the origins of HIV-1 and the reasons for its explosive appearance and rapid transformation into a global epidemic remained a mystery. | AIDS was first described as a new disease in 1981 (MILESTONE 1), and the causative lentivirus that came to be known as HIV-1 was identified a couple of years later (MILESTONE 2). However, the origins of HIV-1 and the reasons for its explosive appearance and rapid transformation into a global epidemic remained a mystery. | ||
=====Tracing the origin and history of the HIV-2 epidemic===== | |||
[https://www.pnas.org/doi/10.1073/pnas.0936469100 by Philippe Lemey, Oliver G. Pybus, Bin Wang, +2 , and Anne-Mieke Vandamme 12/5/03 PNAS] | |||
In this study we date the introduction of HIV-2 into the human population and estimate the epidemic history of HIV-2 subtype A in Guinea-Bissau, the putative geographic origin of HIV-2. The evolutionary history of the simian immunodeficiency virussooty mangabey/HIV-2 lineage was reconstructed by using available database sequences with known sampling dates, and a timescale for this history was calculated by using maximum likelihood methods. | |||
