HIV AIDS: Difference between revisions

Line 121:

[https://www.nature.com/articles/ng.3133 by Orli Bahcall 29/10/14 nature genetics]

Although 13 cases of cross-species transmission of a simian immunodeficiency virus (SIV) into humans have been reported, only HIV-1 group M has led to a pandemic. Oliver Pybus, Philippe Lemey and colleagues now report a phylogenomic analysis of HIV-1 sequences isolated from central Africa, providing insights into what distinguished the origins and spread of HIV-1 group M (Science 346, 56–61, 2014).

=====The causes and consequences of HIV evolution=====

[https://www.nature.com/articles/nrg1246 by Andrew Rambaut 1/1/04 nature reviews genetics]

AIDS is arguably the most serious infectious disease to have affected humankind. Not only are an estimated 42 million people carrying the virus at present1, but its case fatality rate is close to 100%, making it an infection of devastating ferocity. In 2002 alone, 5 million people became infected with the causative agent — the human immunodeficiency virus (HIV) — and, of these, 70% live in sub-Saharan Africa. Although a succession of antiviral agents has made HIV/AIDS a more manageable disease in some industrialized nations, and several vaccines are about to enter Phase III clinical trials, HIV will doubtless continue to impose a terrible burden of morbidity and mortality (Box 1).

HIV AIDS: Difference between revisions

Lilly (talk | contribs)

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 121: / Line 121: @@
 [https://www.nature.com/articles/ng.3133 by Orli Bahcall  29/10/14 nature genetics]
   Although 13 cases of cross-species transmission of a simian immunodeficiency virus (SIV) into humans have been reported, only HIV-1 group M has led to a pandemic. Oliver Pybus, Philippe Lemey and colleagues now report a phylogenomic analysis of HIV-1 sequences isolated from central Africa, providing insights into what distinguished the origins and spread of HIV-1 group M (Science 346, 56–61, 2014).
+=====The causes and consequences of HIV evolution=====
+[https://www.nature.com/articles/nrg1246 by Andrew Rambaut 1/1/04 nature reviews genetics]
+ AIDS is arguably the most serious infectious disease to have affected humankind. Not only are an estimated 42 million people carrying the virus at present1, but its case fatality rate is close to 100%, making it an infection of devastating ferocity. In 2002 alone, 5 million people became infected with the causative agent — the human immunodeficiency virus (HIV) — and, of these, 70% live in sub-Saharan Africa. Although a succession of antiviral agents has made HIV/AIDS a more manageable disease in some industrialized nations, and several vaccines are about to enter Phase III clinical trials, HIV will doubtless continue to impose a terrible burden of morbidity and mortality (Box 1).