Vitamin C: Difference between revisions
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Vitamin C deficiency disrupts the integrity of connective tissues including bone. For decades this function has been primarily attributed to Vitamin C as a cofactor for collagen maturation. Here, we demonstrate that Vitamin C epigenetically orchestrates osteogenic differentiation and function by modulating chromatin accessibility and priming transcriptional activity. | Vitamin C deficiency disrupts the integrity of connective tissues including bone. For decades this function has been primarily attributed to Vitamin C as a cofactor for collagen maturation. Here, we demonstrate that Vitamin C epigenetically orchestrates osteogenic differentiation and function by modulating chromatin accessibility and priming transcriptional activity. | ||
=====Vitamin C and Carbohydrate Metabolism===== | =====Vitamin C and Carbohydrate Metabolism===== | ||
[ | [https://www.nature.com/articles/152329a0 by SACHCHIDANANDA BANERJEE 28/9/1940 nature] | ||
IT has been shown previously1,2 that deficiency of vitamin C in guinea pigs leads to a change in the carbohydrate metabolism as judged by (1) the glycosuria, (2) the diabetic type of the glucose tolerance curve, and (3) the depletion of the glycogen content of the liver. It has also been shown that the normal metabolism of carbohydrate is restored after the administration of vitamin C. From the above evidence, it has been suggested that the action of vitamin C is similar to that of insulin. | |||
Revision as of 10:29, 17 August 2025
Effect of vitamin C supplements on urinary oxalate and pH in calcium stone-forming patients
These data suggest that vitamin C supplementation may increase urinary oxalate excretion and the risk of calcium oxalate crystallization in calcium stone-forming patients.
The Vitamin C Myth
It was Noble Prize Winner Linus Pauling, a chemist, who really popularized vitamin C in the early 60s. He suggested that the vitamin, already known to protect against scurvy, was even more beneficial in mega doses. Dr. Marvin Lipman is an endocrinologist in New York and Chief Medical Advisor for the magazine Consumer Reports.
Sepsis Is A Global Killer. Can Vitamin C Be The Cure?
Every day, approximately 30,000 people die globally of sepsis. The condition comes about when your immune system overreacts to an infection, leading potentially to organ failure and death. There is no cure. But then in 2017, a doctor proposed a novel treatment for sepsis, a mixture that included Vitamin C, arguing it saved the lives of most of his patients. NPR's Richard Harris has been reporting on this treatment and how it's divided scientists from around the world.
Vitamin C 'gives chemotherapy a boost'
by Helen Briggs 9/2/14 BBC NEWS
Pharmaceutical companies are unlikely to run trials, as vitamins cannot be patented.
Vitamin C Fails Again As Treatment For Sepsis
Though attention has understandably been on COVID-19 over the last year, nearly as many people in the hospital have died with a different condition: sepsis. A study now casts doubt on a once-promising treatment for this disease.
How Linus Pauling duped America into believing vitamin C cures colds
by Megan Thielking 27/2/15 Vox
Vitamin C Apparently Not Useful For Sepsis After All
[https://www.npr.org/2021/02/23/970672328/vitamin-c-apparently-not-useful-for-sepsis-after-all by Richard Harris 23/2/21 npr]
The nation's attention has understandably been on COVID-19 over this past year. But in that same span of time, nearly as many people in the hospital have died with a different condition - sepsis. Researchers have been searching for better ways to treat this disease, which is sometimes called blood poisoning. A new study throws cold water on one treatment that had drawn a great deal of interest in the past few years. NPR science correspondent Richard Harris reports.
Dietitians say vitamin C supplements and drinks are a waste of money — eating the right vegetables is a more efficient way to stay healthy
by Allana Akhtar 11/7/22 BUSINESS INSIDER
But data and expert interviews suggest very few Americans need to take vitamin C supplements, particularly those that have far more milligrams than the daily recommendation. Even in cases where a diet could result in low vitamin C, experts told Insider not to rush to the supplement aisle, but rather eat more fruits and veggies.
5 reasons why you should add a vitamin C serum to your skincare routine, according to a dermatologist
by Toketemu Ohwovoriole 10/8/21 BUSINESS INSIDER
Vitamin C is an antioxidant that can benefit all skin types and is one of the best vitamins for your skin. It has numerous benefits, including helping with anti-aging and reversing some of the damage done to your skin by radiation from the sun.
Vitamin C, zinc don’t lessen Covid-19 symptoms, study finds
by Sandee LaMotte 12/2/21 CNN HEALTH
Despite the popular use of vitamin C and zinc to fight off or lessen the severity of viral colds and flu, the new study, published Friday in JAMA Network Open, found the two supplements were of no benefit to people isolating at home with Covid-19.
5 science-backed health benefits of vitamin C and how to add more to your diet
by Nina Bahadur 21/9/21 BUSINESS INSIDER
Vitamin C, also known as ascorbic acid, is used for various processes in the body including building bone, collagen, and muscles. It's also important for wound healing.
Controlling Gangrene; Blood-Starved Tissue Vitalized By Vitamin C and Histidine
This is a digitized version of an article from The Times’s print archive, before the start of online publication in 1996. To preserve these articles as they originally appeared, The Times does not alter, edit or update them.
Cortisone May Aid Arteriosclerosis By Storing Vitamin C in the Blood
by The New York Times 15/9/1950
Cortisone and ACTH may be effective against hardening of the arteries because they facilitate the storage of Vitamin C (ascorbic acid) in the blood and the adrenal glands, experiments reported at the opening of the American Physiological Society's summer meeting at Ohio State University here today indicated.
10 signs you might have a vitamin C deficiency, according to an expert
[https://africa.businessinsider.com/lifestyle/10-signs-you-might-have-a-vitamin-c-
Your body needs vitamin C to help heal wounds, keep your bones and teeth strong, and to help absorb iron in your body. Vitamin C is also used to help create vital proteins that are responsible for making your skin, tendons, ligaments, and blood vessels, according to the US National Library of Medicine . The body needs vitamin C to help a handful of enzymes in the body produce molecules we need every day, like collagen and carnitine.
Ascorbic Acid (Vitamin C)
THE discussion on ascorbic acid (vitamin C) which was held in Section B (Chemistry) at the recent meeting of the British Association was, as the official title of the discussion indicated, mainly devoted to the chemical aspect of the subject.
Association between vitamin C in serum and trouble sleeping based on NHANES 2017–2018
by Shihong Wang 27/4/24 scientific reports
Vitamin C is an important micronutrient for human. Association between vitamin C and trouble sleeping was less studied. Therefore, the purpose of this study was to investigate the possible link between vitamin C in serum and trouble sleeping.
The role of vitamin C in pneumonia and COVID-19 infection in adults with European ancestry: a Mendelian randomisation study
by European Journal of Clinical Nutrition 30/8/21 EJCN
Genetically predicted circulating levels of vitamin C was not associated with susceptibility to severe COVID-19, COVID-19 hospitalisation, any COVID-19 infection nor pneumonia. Similar results were obtained when a weighted median and MR-Egger methods were used.
Vitamin C epigenetically controls osteogenesis and bone mineralization
by Roman Thaler 6/10/22 nature communications
Vitamin C deficiency disrupts the integrity of connective tissues including bone. For decades this function has been primarily attributed to Vitamin C as a cofactor for collagen maturation. Here, we demonstrate that Vitamin C epigenetically orchestrates osteogenic differentiation and function by modulating chromatin accessibility and priming transcriptional activity.
Vitamin C and Carbohydrate Metabolism
by SACHCHIDANANDA BANERJEE 28/9/1940 nature
IT has been shown previously1,2 that deficiency of vitamin C in guinea pigs leads to a change in the carbohydrate metabolism as judged by (1) the glycosuria, (2) the diabetic type of the glucose tolerance curve, and (3) the depletion of the glycogen content of the liver. It has also been shown that the normal metabolism of carbohydrate is restored after the administration of vitamin C. From the above evidence, it has been suggested that the action of vitamin C is similar to that of insulin.
