AHCC: Difference between revisions
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Created page with "=====The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies===== [https://onlinelibrary.wiley.com/doi/10.1155/2019/3758576 by Min Sun Shin, Hong-Jai Park, Takahiro Maeda, Hiroshi Nishioka, Hajime Fujii, Insoo Kang 20/12/2019 Journal of Immunology Research] Mushrooms have been used for various health conditions for many years by traditional medicines pr..." |
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[https://www.sciencedirect.com/science/article/abs/pii/S0024320513006590 by Mehran Haidari 18/12/13 ScienceDirect] | [https://www.sciencedirect.com/science/article/abs/pii/S0024320513006590 by Mehran Haidari 18/12/13 ScienceDirect] | ||
The effect of antioxidants on treatment of cancer is still controversial. Previously, we demonstrated that interaction of breast cancer cells with endothelial cells leads to tyrosine phosphorylation of VE-cadherin and disruption of endothelial adherens junction (EAJ). The molecular mechanism underlying the anti-metastatic effects of mushroom-derived active hexode correlated compound (AHCC) remains elusive. | The effect of antioxidants on treatment of cancer is still controversial. Previously, we demonstrated that interaction of breast cancer cells with endothelial cells leads to tyrosine phosphorylation of VE-cadherin and disruption of endothelial adherens junction (EAJ). The molecular mechanism underlying the anti-metastatic effects of mushroom-derived active hexode correlated compound (AHCC) remains elusive. | ||
===== | =====Active Hexose Correlated Compound (AHCC) has direct immunomodulatory actions===== | ||
[https://www.sciencedirect.com/science/article/abs/pii/S0308814612014410 by Abdelali Daddaoua 15/2/13 ScienceDirect] | [https://www.sciencedirect.com/science/article/abs/pii/S0308814612014410 by Abdelali Daddaoua 15/2/13 ScienceDirect] | ||
Active Hexose Correlated Compound (AHCC) is an immunostimulatory nutritional supplement. AHCC effects and mechanism of action on intestinal epithelial cells or monocytes are poorly described. AHCC was added to the culture medium of intestinal epithelial cells (IEC18 and HT29 cells) and monocytes (THP-1 cells) and assessed the secretion of proinflammatory cytokines by ELISA. Inhibitors of NFκB and MAPKs were used to study signal transduction pathways while TLR4 and MyD88 were silenced in IEC18 cells using shRNA. | Active Hexose Correlated Compound (AHCC) is an immunostimulatory nutritional supplement. AHCC effects and mechanism of action on intestinal epithelial cells or monocytes are poorly described. AHCC was added to the culture medium of intestinal epithelial cells (IEC18 and HT29 cells) and monocytes (THP-1 cells) and assessed the secretion of proinflammatory cytokines by ELISA. Inhibitors of NFκB and MAPKs were used to study signal transduction pathways while TLR4 and MyD88 were silenced in IEC18 cells using shRNA. | ||
=====Active Hexose Correlated Compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1β production from monocytes in humans===== | =====Active Hexose Correlated Compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1β production from monocytes in humans===== | ||
[https://www.sciencedirect.com/science/article/abs/pii/S0008874912000603 by Won-Woo Lee 2/12 ScienceDirect] | [https://www.sciencedirect.com/science/article/abs/pii/S0008874912000603 by Won-Woo Lee 2/12 ScienceDirect] | ||
