Vitamin C
From WikiDemocracy
Effect of vitamin C supplements on urinary oxalate and pH in calcium stone-forming patients
These data suggest that vitamin C supplementation may increase urinary oxalate excretion and the risk of calcium oxalate crystallization in calcium stone-forming patients.
The Vitamin C Myth
It was Noble Prize Winner Linus Pauling, a chemist, who really popularized vitamin C in the early 60s. He suggested that the vitamin, already known to protect against scurvy, was even more beneficial in mega doses. Dr. Marvin Lipman is an endocrinologist in New York and Chief Medical Advisor for the magazine Consumer Reports.
Sepsis Is A Global Killer. Can Vitamin C Be The Cure?
Every day, approximately 30,000 people die globally of sepsis. The condition comes about when your immune system overreacts to an infection, leading potentially to organ failure and death. There is no cure. But then in 2017, a doctor proposed a novel treatment for sepsis, a mixture that included Vitamin C, arguing it saved the lives of most of his patients. NPR's Richard Harris has been reporting on this treatment and how it's divided scientists from around the world.
Vitamin C 'gives chemotherapy a boost'
by Helen Briggs 9/2/14 BBC NEWS
Pharmaceutical companies are unlikely to run trials, as vitamins cannot be patented.
Vitamin C Fails Again As Treatment For Sepsis
Though attention has understandably been on COVID-19 over the last year, nearly as many people in the hospital have died with a different condition: sepsis. A study now casts doubt on a once-promising treatment for this disease.
How Linus Pauling duped America into believing vitamin C cures colds
by Megan Thielking 27/2/15 Vox
Vitamin C Apparently Not Useful For Sepsis After All
[https://www.npr.org/2021/02/23/970672328/vitamin-c-apparently-not-useful-for-sepsis-after-all by Richard Harris 23/2/21 npr]
The nation's attention has understandably been on COVID-19 over this past year. But in that same span of time, nearly as many people in the hospital have died with a different condition - sepsis. Researchers have been searching for better ways to treat this disease, which is sometimes called blood poisoning. A new study throws cold water on one treatment that had drawn a great deal of interest in the past few years. NPR science correspondent Richard Harris reports.
Dietitians say vitamin C supplements and drinks are a waste of money — eating the right vegetables is a more efficient way to stay healthy
by Allana Akhtar 11/7/22 BUSINESS INSIDER
But data and expert interviews suggest very few Americans need to take vitamin C supplements, particularly those that have far more milligrams than the daily recommendation. Even in cases where a diet could result in low vitamin C, experts told Insider not to rush to the supplement aisle, but rather eat more fruits and veggies.
5 reasons why you should add a vitamin C serum to your skincare routine, according to a dermatologist
by Toketemu Ohwovoriole 10/8/21 BUSINESS INSIDER
Vitamin C is an antioxidant that can benefit all skin types and is one of the best vitamins for your skin. It has numerous benefits, including helping with anti-aging and reversing some of the damage done to your skin by radiation from the sun.
Vitamin C, zinc don’t lessen Covid-19 symptoms, study finds
by Sandee LaMotte 12/2/21 CNN HEALTH
Despite the popular use of vitamin C and zinc to fight off or lessen the severity of viral colds and flu, the new study, published Friday in JAMA Network Open, found the two supplements were of no benefit to people isolating at home with Covid-19.
5 science-backed health benefits of vitamin C and how to add more to your diet
by Nina Bahadur 21/9/21 BUSINESS INSIDER
Vitamin C, also known as ascorbic acid, is used for various processes in the body including building bone, collagen, and muscles. It's also important for wound healing.
Controlling Gangrene; Blood-Starved Tissue Vitalized By Vitamin C and Histidine
This is a digitized version of an article from The Times’s print archive, before the start of online publication in 1996. To preserve these articles as they originally appeared, The Times does not alter, edit or update them.
Cortisone May Aid Arteriosclerosis By Storing Vitamin C in the Blood
by The New York Times 15/9/1950
Cortisone and ACTH may be effective against hardening of the arteries because they facilitate the storage of Vitamin C (ascorbic acid) in the blood and the adrenal glands, experiments reported at the opening of the American Physiological Society's summer meeting at Ohio State University here today indicated.
10 signs you might have a vitamin C deficiency, according to an expert
[https://africa.businessinsider.com/lifestyle/10-signs-you-might-have-a-vitamin-c-
Your body needs vitamin C to help heal wounds, keep your bones and teeth strong, and to help absorb iron in your body. Vitamin C is also used to help create vital proteins that are responsible for making your skin, tendons, ligaments, and blood vessels, according to the US National Library of Medicine . The body needs vitamin C to help a handful of enzymes in the body produce molecules we need every day, like collagen and carnitine.
Ascorbic Acid (Vitamin C)
THE discussion on ascorbic acid (vitamin C) which was held in Section B (Chemistry) at the recent meeting of the British Association was, as the official title of the discussion indicated, mainly devoted to the chemical aspect of the subject.
Association between vitamin C in serum and trouble sleeping based on NHANES 2017–2018
by Shihong Wang 27/4/24 scientific reports
Vitamin C is an important micronutrient for human. Association between vitamin C and trouble sleeping was less studied. Therefore, the purpose of this study was to investigate the possible link between vitamin C in serum and trouble sleeping.
The role of vitamin C in pneumonia and COVID-19 infection in adults with European ancestry: a Mendelian randomisation study
by European Journal of Clinical Nutrition 30/8/21 EJCN
Genetically predicted circulating levels of vitamin C was not associated with susceptibility to severe COVID-19, COVID-19 hospitalisation, any COVID-19 infection nor pneumonia. Similar results were obtained when a weighted median and MR-Egger methods were used.
Vitamin C epigenetically controls osteogenesis and bone mineralization
by Roman Thaler 6/10/22 nature communications
Vitamin C deficiency disrupts the integrity of connective tissues including bone. For decades this function has been primarily attributed to Vitamin C as a cofactor for collagen maturation. Here, we demonstrate that Vitamin C epigenetically orchestrates osteogenic differentiation and function by modulating chromatin accessibility and priming transcriptional activity.
Vitamin C and Carbohydrate Metabolism
by SACHCHIDANANDA BANERJEE 28/9/1940 nature
IT has been shown previously1,2 that deficiency of vitamin C in guinea pigs leads to a change in the carbohydrate metabolism as judged by (1) the glycosuria, (2) the diabetic type of the glucose tolerance curve, and (3) the depletion of the glycogen content of the liver. It has also been shown that the normal metabolism of carbohydrate is restored after the administration of vitamin C. From the above evidence, it has been suggested that the action of vitamin C is similar to that of insulin.
Supplies of Vitamin C
TATEMENTS have recently appeared in the German scientific press to the effect that German men of science have discovered that the hips of the wild rose are a rich source of the antiscorbutic vitamin C, and that the German State railways have arranged to grow wild roses along the tracks.
Apparent Vitamin C in Walnuts
by RONALD MELVILLE 16/10/1943 nature
THE remarkably high vitamin C content of walnuts has been mentioned by various workers1,2. Recent work3,4 indicates that foods may contain substances which react with the dye and are estimated as ascorbic acid under the usual titration conditions but are not true vitamin C.
Vitamin C exhibits pro-oxidant properties
by Ian D. Podmore 9/4/98 nature
Vitamin C is marketed as a dietary supplement, partly because of its ‘antioxidant’ properties. However, we report here that vitamin C administered as a dietary supplement to healthy humans exhibits a pro-oxidant, as well as an antioxidant, effect in vivo.
Vitamin C deficiency causes muscle atrophy and a deterioration in physical performance
by Shoko Takisawa 20/3/19 scientific reports
L-Ascorbic acid (AsA) is a water-soluble antioxidant. We examined the effect of AsA deficiency on skeletal muscle using senescence marker protein-30 (SMP30)-knockout (KO) mice that are defective in AsA biosynthesis, which makes this mouse model similar to humans, to clarify the function of AsA in skeletal muscle. Eight-week-old female SMP30-KO mice were divided into the following two groups: an AsA-sufficient group [AsA(+)] that was administered 1.5 g/L AsA and an AsA-deficient group [AsA(−)] that was administered tap (AsA-free) water.
What The Heck Does Vitamin C Serum Do For Your Skin, Anyway?
by Brittany Nims 21/6/19 HUFFPOST
These days people are turning to Vitamin C to give their lackluster complexion a juicy glow. Sephora’s best Vitamin C serums promise results for dry skin, oily skin, acne scars, fine lines and wrinkles, and even dark spots and sun damage. Those are some big promises for small bottles.
Sorry, Your Vitamin C Megadose Is Basically Useless
[https://www.huffpost.com/entry/emergen-c-airborne-does-it-work_n_55f3709ee4b063ecbfa486c8 by Anna Almendrala 5/1/18 HUFFPOST]
To avoid a cold or cut one short, you may be tempted to stock up on supplemental drink mix-ins like Emergen-C and Airborne for supposed cold-fighting ingredients like vitamin C or zinc. But do these unregulated powders and tablets actually work?
Should You Take Extra Vitamins To Prevent Coronavirus Infection?
by Jenna Birch 6/5/20 HUFFPOST
From the start of the coronavirus pandemic, there has been a focus on wellness, and ways to avoid becoming seriously ill. One of the methods people are relying on is taking vitamins targeted to bolstering immunity.
Turns Out Oranges Aren't The Best Source Of Vitamin C, After All
by Julie R. Thomson 6/1/17 HUFFPOST
It’s that time of year. The time of year when everyone around us is sick and all us healthy people are popping Emergen-Cs and vitamin C tablets in a desperate attempt to try to remain well. Here’s the thing you should know: despite the commonly held belief, vitamin C doesn’t actually help you fight a cold ― it took 50 years of research to conclude that.
On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence
by Jens Lykkesfeldt 6/20 science direct
For decades, the potential beneficial effect of vitamin C on human health—beyond that of preventing scurvy—has been subject of much controversy. Hundreds of articles have appeared either in support of increased vitamin C intake through diet or supplements or rejecting the hypothesis that increased intake of vitamin C or supplementation may influence morbidity and mortality.
The Long History of Vitamin C: From Prevention of the Common Cold to Potential Aid in the Treatment of COVID-19
by Ioannis Zabetakis 27/10/20 frontiers
From Pauling’s theories to the present, considerable understanding has been acquired of both the physiological role of vitamin C and of the impact of vitamin C supplementation on the health. Although it is well known that a balanced diet which satisfies the daily intake of vitamin C positively affects the immune system and reduces susceptibility to infections, available data do not support the theory that oral vitamin C supplements boost immunity.
The Mystery of Vitamin C
Also known as ascorbic acid, vitamin C is a small carbohydrate molecule first identified in the 1920s by Albert von Szent Györgyi, who discovered that it was able to prevent and cure scurvy. Scurvy is a pathological life-threatening condition suffered by people who do not have access to fruits or vegetables for long periods of time. A decade earlier, Kazimierz Funk had prepared a list of nutritional factors, called vitamins, whose deficiencies cause severe diseases in humans. In his list, Funk used the letter "C" to designate a factor still unidentified, but known to prevent scurvy. Later on, Szent Györgyi and Haworth chemically identified "C" as ascorbic acid, and named it so because ascorbic means "anti-scurvy." Over the next century, what we now know as vitamin C became one of the most popular drugs in human history.
The role of vitamin C in stress-related disorders
by Bettina Moritz 11/20 Sciencedirect
Stress-related disorders, such as depression and anxiety, present marked deficits in behavioral and cognitive functions related to reward. These are highly prevalent disabling conditions with high social and economic costs.
Vitamin C Deficiency
Vitamin C deficiency, commonly called scurvy, is a well-documented nutritional disorder with historical significance that continues to impact global health today. Vitamin C is an essential nutrient for maintaining an individual's good health and well-being.
