Diabetes

The importance of exercise for glycemic control in type 2 diabetes

by U.S. Afsheen Syeda 6/23 ScienceDirect

Exercise is a first-line therapy recommended for patients with type 2 diabetes (T2D). Although moderate to vigorous exercise (e.g. 150 min/wk) is often advised alongside diet and/or behavior modification, exercise is an independent treatment that can prevent, delay or reverse T2D. 

Statin users have an elevated risk of dysglycemia and new-onset-diabetes

by Victoria A. Zigmont 24/5/19 WILEY

Statins are one of the most widely prescribed medications in the United States; however, there is a concern that they are associated with new-onset-diabetes (NOD) development. We sought to understand the risk of dysglycemia and NOD for a cohort of individuals that reflect real-world physician prescribing patterns.

The Relationship of Sugar to Population-Level Diabetes Prevalence: An Econometric Analysis of Repeated Cross-Sectional Data

by Sanjay Basu 27/2/13 PLUS. One

While experimental and observational studies suggest that sugar intake is associated with the development of type 2 diabetes, independent of its role in obesity, it is unclear whether alterations in sugar intake can account for differences in diabetes prevalence among overall populations

Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings

by Adrienne R. Barnosky 10/14 ScienceDirect

Intermittent fasting (IF) regimens have gained considerable popularity in recent years, as some people find these diets easier to follow than traditional calorie restriction (CR) approaches. IF involves restricting energy intake on 1–3 d/wk, and eating freely on the nonrestriction days. Alternate day fasting (ADF) is a subclass of IF, which consists of a “fast day” (75% energy restriction) alternating with a “feed day” (ad libitum food consumption). 

Vinegar Consumption Increases Insulin-Stimulated Glucose Uptake by the Forearm Muscle in Humans with Type 2 Diabetes

by Panayota Mitrou 6/5/15 WILEY

A mixture of vinegar and olive oil is a common salad dressing used in the Mediterranean diet. The main constituent of vinegar is acetic acid, which gives vinegar its characteristic taste and smell. The consumption of vinegar with meals was used as a folk medicine for the treatment of diabetes before any pharmacologic glucose-lowering therapy [1, 2]. Recent studies indicate that vinegar improves insulin sensitivity in healthy volunteers, as well as in subjects with diabetes

Late eating is associated with poor glucose tolerance, independent of body weight, fat mass, energy intake and diet composition in prediabetes or early onset type 2 diabetes

by Diana A. Díaz-Rizzolo 25/10/24 Nutrition & Diabetes

This study investigates the impact of habitual late calorie intake on glucose metabolism in adults with overweight or obesity and diet or metformin-controlled prediabetes or type 2 diabetes independently of body weight, fat mass, energy intake or diet composition. 

In the SELECT cardiovascular outcomes trial, semaglutide showed a 20% reduction in major adverse cardiovascular events in 17,604 adults with preexisting cardiovascular disease, overweight or obesity, without diabetes.

by Richard D. Feinman Ph.D. 1/15 ScienceDirect

The inability of current recommendations to control the epidemic of diabetes, the specific failure of the prevailing low-fat diets to improve obesity, cardiovascular risk, or general health and the persistent reports of some serious side effects of commonly prescribed diabetic medications, in combination with the continued success of low-carbohydrate diets in the treatment of diabetes and metabolic syndrome without significant side effects, point to the need for a reappraisal of dietary guidelines.

Long-term weight loss effects of semaglutide in obesity without diabetes in the SELECT trial

by Donna H. Ryan 13/5/24 nature medicine

In the SELECT cardiovascular outcomes trial, semaglutide showed a 20% reduction in major adverse cardiovascular events in 17,604 adults with preexisting cardiovascular disease, overweight or obesity, without diabetes. 

Diabetes risk soars for adults who had a sweet tooth as kids

by Heidi Ledford 31/10/24 nature

It’s tough news to hear on Halloween: a sugary diet in the first two years of life is linked to a higher risk of type 2 diabetes and high blood pressure decades later, according to an analysis of UK sugar rationing in the 1950s.

Red meat intake and risk of type 2 diabetes in a prospective cohort study of United States females and males

by Xiao Gu 12/23 ScienceDirect

Studies with methodological advancements are warranted to confirm the relation of red meat consumption to the incidence of type 2 diabetes (T2D).

What is diabetes?

by Aoife M. Egan 1/19 Science Direct

Diabetes mellitus represents a set of autoimmune, metabolic and genetic disorders that share one major characteristic – hyperglycaemia. The recommended way of measuring plasma glucose and the threshold used to define what is normal or abnormal have gone through several iterations over the past few decades. 

by Richa Patel; Reddog E. Sina; Daniel Keyes 12/02/24 National Library of Medicine

Two of the most prevalent diseases worldwide are type 2 diabetes mellitus (T2DM) and coronary artery disease. T2DM occurs when there is a decrease in insulin sensitivity, leading to higher amounts of glucose being present in the bloodstream. Coronary artery disease, or heart disease, develops over time as plaque builds up within the coronary arteries, causing a higher likelihood of developing myocardial infarction in the future. Though both of these conditions have specific disease processes, developing T2DM has been associated with a significantly higher incidence of developing coronary artery disease.