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| =====The Effects of AHCC®, a Standardized Extract of Cultured Lentinura edodes Mycelia, on Natural Killer and T Cells in Health and Disease: Reviews on Human and Animal Studies=====
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| [https://onlinelibrary.wiley.com/doi/10.1155/2019/3758576 by Min Sun Shin, Hong-Jai Park, Takahiro Maeda, Hiroshi Nishioka, Hajime Fujii, Insoo Kang 20/12/2019 Journal of Immunology Research] | | [[Vitamin D]] |
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| Mushrooms have been used for various health conditions for many years by traditional medicines practiced in different regions of the world although the exact effects of mushroom extracts on the immune system are not fully understood. AHCC® is a standardized extract of cultured shiitake or Lentinula edodes mycelia (ECLM) which contains a mixture of nutrients including oligosaccharides, amino acids, and minerals obtained through liquid culture. AHCC® is reported to modulate the numbers and functions of immune cells including natural killer (NK) and T cells which play important roles in host defense, suggesting the possible implication of its supplementation in defending the host against infections and malignancies via modulating the immune system. Here, we review in vivo and in vitro effects of AHCC® on NK and T cells of humans and animals in health and disease, providing a platform for the better understanding of immune-mediated mechanisms and clinical implications of AHCC®.
| | [[AHCC]] |
| =====AHCC® Supplementation to Support Immune Function to Clear Persistent Human Papillomavirus Infections=====
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| [https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2022.881902/full by Judith A. Smith 21/6/22 frontiers] | | [[Vitamin C]] |
| Objective: To determine the efficacy, safety, and durability of the use of AHCC supplementation for 6 months to support the host immune system to clear high-risk human papillomavirus (HPV) infections. The AHCC supplement is a proprietary, standardized extract of cultured lentinula edodes mycelia (AHCC®, Amino Up, Ltd., Sapporo, Japan) that has been shown to have unique immune modulatory benefits.
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| =====Lentinula edodes extract increases goblet cell number and Muc2 expression in an intestinal inflammatory model of Trichinella spiralis infection=====
| | [[Probiotics]] |
| [https://www.sciencedirect.com/science/article/pii/S0753332222003262 by Beatriz López-Cauce 6/22 ScienceDirect] | | |
| AHCC® is a standardized extract of cultured mushroom (Lentinula edodes) mycelia with a wide variety of therapeutic effects including anti-inflammatory, antitumor and antiviral effects. Trichinellosis, a food-borne parasitic zoonosis is caused by the nematode Trichinella spp. Infection with Trichinella is characterized by the induction of a Th1-type response at the beginning of the intestinal phase, followed by a dominant Th2-type response which is essential for parasite expulsion.
| | [[Nutritional Yeast]] |
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| | [[Multivitamins]] |